Tuesday, January 24, 2017

Non small cell lung cancer- treatment option and prognosis

non small cell lung cancer, prognosis for stage 4 lung cancer,  what is non small cell lung cancer, chemotherapy for lung cancer, non small cell lung cancer prognosis

Cancer or carcinoma an important cause of death from non-infectious disease around the world can affect almost any organ or tissue & the incidence of which is showing the trend of increasing rather than decreasing although there is progress being made everyday with clinical and public health. Lung cancer remains the most common cancer among both sexes, holding the top position among males and third position among females and most importantly holding the position of most common cause of cancer death around the world with 1.59 million death in 2012 according to WHO. 

The incidence is on the rise with the increased use of tobacco specially in the developing world and increased air pollution due to rapid industrialisation with more focus on profit and growth and little interest in human life and environment. Lung cancers are divided in 2 groups therapeutically, non small cell lung cancer (NSCLC) and the deadlier Small cell lung cancer (SCLC).

Small cell carcinoma of lung is divided into mainly two stages, the limited stage (I-III) and extensive stage (IV) small cell lung cancer. 

SCLC is more responsive to chemotherapy and radiation therapy than other cell types of lung cancer; however, a cure is difficult to achieve because SCLC has a greater tendency to be widely disseminated by the time of diagnosis and majority of the patients are stage IV. 

The first line chemotherapeutic recommendation is carboplatin or cisplatin with etoposide or irinotecan. Another option is doxorubicin plus vincristine with cyclophosphamide. 

Chemotherapeutics should be used maximum 4-6 cycle. Second line chemotherapy includes is used if patient relapses or remains refractory. If the relapse occurs after 6months or more disease free survival then the original first line chemotherapeutics can be repeated with 60-100% response rate. 

If otherwise then single or combination of carboplatin, cisplatin, irinotecan, etoposide, paclitaxel, topotecan can be used. If these fail then another of these agents can be used as third line. 

Prophylactic cranial radiation prevents central nervous system recurrence and can improve survival in patients with good performance status who have had a complete response or a very good partial response to chemotherapy in stage IV disease. Despite these treatments In patients with stage IV median survival of 6 to 12 months is reported with currently available therapy, and  long-term disease-free survival is rare. All patients with this type of cancer may appropriately be considered for inclusion in clinical trials at the time of diagnosis.

Wednesday, January 18, 2017

Stage 4 lung cancer treatment

stage 4 lung cancer treatment, lung cancer treatment, non small cell lung cancer, lung cancer stage 4, metastatic lung cancer

Written by:     Dr. Julfikar Saif
                     Bachelor of medicine Bachelor of Surgery

Non small cell lung cancer is a term that includes adenocarcinoma of lung, squamous cell carcinoma of lung and large cell carcinoma of lung. It is considered to be stage IV when already tumor spreading to distant location or metastasis has taken place. 

Monday, January 9, 2017

Bad smell from foot, cause and prevention

smell feet, causes of smelly feet, what causes feet to smell, sweaty feet causes, sweaty feet cure, get rid of foot odor, smelly sweaty feet solutions, cure to smelly feet

Bad smell from foot, cause and prevention

Many people suffer from bad odors from foot. Many times it’s very embarrassing. To solve the problem we need to know the reason behind it.
Let’s see, what the mechanism behind it is.

Thursday, January 5, 2017


common allergies, allergy information,

Allergy ѕеаѕоn is now in full ѕwіng, аnd реорlе еvеrуwhеrе аrе lооkіng fоr tірѕ to gеt rіd оf аllеrgy.This аrtісlе will discuss fіvе оf thе most соmmоn аllеrgіеѕ аnd tips оn how to gеt rid оf thеm.

Tuesday, January 3, 2017

Natural ways to fight allergies

allergy remedies at home, allergy relief at home,natural ways to cure allergies, natural ways to fight allergies,

Allergies hаvе gripped thе whоlе wоrld. It'ѕ dіѕсоvеrеd thаt every оnе іn 4 Amеrісаnѕ іѕ being affected bу оnе оr another fоrm of аllеrgу. Allеrgіеѕ tаkе рlасе whenever thе immune ѕуѕtеm of оur оwn bоdу detects аnу ѕоrt of substance as a foreign body.